A database of hormones and their receptors
Peptide Hormone

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HMRbase accession number10518
Swiss-prot Accession numberQ9VLK4 (Sequence in FASTA format)
DescriptionDiuretic hormone class-II precursor (Diuretic peptide) (DP) (DH(31)).
Source organismDrosophila melanogaster (Fruit fly)
Taxonomical ClassificationEukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the diuretic hormone class II family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionRegulation of fluid secretion. Stimulates Malpighian tubules fluid secretion by activating the apical membrane V-ATPase via cyclic AMP of principal cells in the main secretory segment
Protein Length116 Amino acids
Molecular weight12622
References1  PubMed abstract 10731132
2  PubMed abstract 12537572
3   Stapleton M., Carlson J.W., Chavez C., Frise E., George R.A.,Pacleb J.M., Park S., Wan K.H., Yu C., Rubin G.M., Celniker S.E.; Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.
4  PubMed abstract 11316500
Domain NameN/A
Hormone NameDiuretic hormone class-II
Mature Hormone SequenceTVDFGLARGYSGTQEAKHRMGLAAANFAGGP
Position of mature hormone in Pre-Hormone protein31 Residues from position (76-106)
ReceptorN/A
Gene ID34181      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated